Abstract： Diabetic kidney disease （DKD） is a severe microvascular complication of diabetes mellitus， characterized by insidious onset， protracted progression， and eventually leading to renal failure. Although modern medicine has achieved advances in controlling blood glucose，blood pressure，and proteinuria，it remains difficult to completely halt disease progression. In traditional Chinese medicine，DKD falls under the categories of wasting-thirst， edema， and blockage and repulsion. Based on classical traditional Chinese medicine texts and contemporary clinical practice，Chief Physician WANG Wenfeng proposes that healthy qi deficiency accumulation damage constitutes the core pathogenesis of DKD. This article systematically elaborates on the application of this theory in the diagnosis and treatment of DKD from three aspects： theoretical origins， pathogenic evolution， and clinical differentiation. It delineates the pathological process of deficiency giving rise to accumulation， accumulation generating toxins， and toxins damaging the body and impairing function， and advocates that the therapeutic approach should center on fortifying the healthy qi to repair damage and attacking toxins to eliminate accumulations， aiming to provide new insights for clinical management.