Abstract：Objective：To explore the correlation between clinical characteristics of sudden sensorineural hearing loss（ SSHL） patients and traditional Chinese medicine syndrome types，and to provide objective reference indicators for traditional Chinese medicine syndrome differentiation. Methods： A retrospective study was conducted on SSHL inpatients admitted to The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine from January 2022 to December 2024. Clinical data and traditional Chinese medicine syndrome types were collected. Relevant indicators were screened through univariate analysis， and a multivariate logistic regression model was constructed. Receiver operating characteristic （ROC） curves were plotted to evaluate the predictive performance of the model. Results： A total of 151 SSHL patients were finally included， in terms of the traditional Chinese medicine syndrome types，the qi stagnation and blood stasis type being the most prevalent（ 62 cases，41.06%），followed by the external pathogen invasion type （49 cases， 32.45%）， the phlegm-fire stagnation type （26 cases，17.22%），and the liver fire flaring upward type （14 cases， 9.27%）. Significant overall differences were found among patients with different traditional Chinese medicine syndrome types in terms of brain magnetic resonance （MR） abnormality rate， cervical vascular ultrasound abnormality rate， total cholesterol （TC）， triglycerides （TG）， low-density lipoprotein cholesterol （LDL-C）， and fasting blood glucose （FBG） levels （P＜0.05）. Patients with the qi stagnation and blood stasis type had significantly higher TC and LDL-C levels than those with other syndrome types （P＜0.05）， while no elevation was observed in TG. Multivariate logistic regression showed that both TC [OR=2.009， 95% CI （1.292- 3.125） ] and LDL-C [OR=6.209，95% CI （3.193-12.076）] were independent predictors of the qi stagnation and blood stasis type （P＜0.01）. ROC curve analysis showed that the area under the curve （AUC） of LDL-C was 0.839 [95% CI （0.772-0.905）]，with a sensitivity of 79.0% and specificity of 84.3%. After combining with TC，the AUC increased to 0.865 [95% CI （0.807-0.923）]. Conclusion： LDL-C can serve as an auxiliary discriminatory indicator for the qi stagnation and blood stasis type of SSHL，with the optimal diagnostic efficacy at LDL-C ≥ 2.91 mmol/L. This provides a laboratory basis for the objective differentiation of traditional Chinese medicine syndromes.