Abstract： Objective： To observe the application effect of a comprehensive traditional Chinese medicine health management model in patients with metabolic abnormalities after breast cancer surgery based on the "treating disease before it arises" theory. Methods： A total of 128 patients with metabolic abnormalities after breast cancer surgery admitted to Hangzhou Linping District Maternal and Child Health Hospital from June 2022 to June 2024 were selected as study subjects and randomly divided into a conventional group and a comprehensive traditional Chinese medicine group using a random number table method， with 64 cases in each group. The conventional group received routine postoperative intervention for breast cancer； the comprehensive traditional Chinese medicine group received intervention based on the comprehensive traditional Chinese medicine health management model under the "treating disease before it arises" theory. All patients were continuously intervened for one year. Fasting blood glucose （FBG）， anthropometric indicators [systolic blood pressure， diastolic blood pressure， waist circumference （WC）， body mass index （BMI）]， blood lipid indicators [total cholesterol （TC）， triglycerides （TG）， high-density lipoprotein cholesterol（ HDL-C），low-density lipoprotein cholesterol（ LDL-C）]，quality of life [Functional Assessment of Cancer Therapy-Breast （FACT-B）]， and self-management ability were compared between the two groups before and after intervention. Results： After treatment， FBG levels decreased in both groups compared to before intervention （P＜ 0.05）， and the comprehensive traditional Chinese medicine group had lower FBG levels than the conventional group （P＜0.05）. After treatment， TC， TG， and LDL-C levels decreased in both groups compared to before intervention （P＜0.05）， while HDL-C levels increased （P＜0.05）. The comprehensive traditional Chinese medicine group had lower TC，TG，and LDL-C levels and higher HDL-C levels than the conventional group （P＜0.05）. After treatment， systolic blood pressure， diastolic blood pressure， WC， and BMI decreased in both groups compared to before intervention （P＜0.05），and the comprehensive traditional Chinese medicine group had lower levels of all four indicators than the conventional group （P＜0.05）. After treatment， FACT-B and self-management ability scores increased in both groups compared to before intervention （P＜0.05）， and the comprehensive traditional Chinese medicine group had higher scores than the conventional group （P＜0.05）. No severe adverse events occurred in either group during treatment. Conclusion： The comprehensive traditional Chinese medicine health management model can more effectively improve glucose and lipid metabolism，overall nutrition，quality of life，and self-management ability in patients with metabolic abnormalities after breast cancer surgery，with a favorable safety profile.