Abstract：This paper introduces Professor LIANG Xuefang's clinical experience in treating endometriosis based on the core traditional Chinese medicine theory that qi is the commander of blood. In the view of Professor LIANG， the basic pathogenesis of endometriosis is qi deficiency and blood stasis， emphasizing that the root cause lies in root deficiency of spleen and kidney. Therefore， she adopts tonifying qi and eliminating masses as the general treatment principle. In clinical practice，she treats the root by invigorating the spleen and replenishing qi，as well as tonifying the kidney and consolidating the origin，while treating the manifestation by resolving stasis and eliminating masses，thus simultaneous application of purging and nourishing therapeutics is stressed. Moreover，she adapts treatment according to seasonal and regional factors： following the menstrual cycle therapy with regard to time， and selecting authentic Lingnan area Chinese herbal medicinals with regard to region，often achieving certain results.